‘don’t Ignore Stomach Pain And Indigestion’

Supine GERD patients with large breaks experienced higher acid exposure, prolonged bolus clearance

He said that Korea had high incidence of gastric cancer in the world. More than 60 per cent of it had been detected at an early stage as there was awareness about the disease among the people. We have high incidence of gastric cancer in Korea because people use a lot of salt in their food. Thirty years ago, only 20 per cent of cases were detected early. Today, after creating awareness through mass media and offering free screening for people, more than 60 per cent of cases are detected early. People in Korea get screened once in every two years, the professor informed. In India, 90 per cent of cases are detected when the cancer is at an advanced stage. Thats the big problem. The doctors find they cant do anything about the cancer only after they open the stomach during surgery, the professor added. Pointing out that there was lack of awareness on gastric cancer in India, the professor warned that people should not ignore symptoms of abdominal pain, indigestion, loss of appetite or black stool, and consult a doctor immediately. He further advised that people should go for endoscopy or gastroscopy for early diagnosis. The best way to save yourself from gastric cancer is to avoid salty food, eat fresh fruits and vegetables, stop smoking and drinking, Yang advised. The professor clarified doubts pertaining to gastric cancer when he spoke about lifestyle changes that could lead to gastric cancer. Smoking and alcohol consumption are dangerous. Especially smoking, it has all kinds of carcinogens that affect not only the lungs, but also the stomach and bladder.

online http://www.newindianexpress.com/cities/chennai/Dont-Ignore-Stomach-Pain-and-Indigestion/2014/01/29/article2025023.ece

Researchers used high-resolution manometry to study the esophageal motility of 40 patients (mean age, 44 years; 26 women) with recurrent gastroesophageal reflux disease ( GERD ) symptoms but no evidence of hiatal hernia. All patients had at least two incidents of vomiting weekly and/or heartburn that lasted for more than 6 months. Patients extended breaks of esophageal peristalis and delayed bolus clearance also were measured by 24-hour multichannel impedance-pH to determine if a relationship existed. Both total bolus clearing time, while patients were in upright and supine positions, and acid exposure time (AET) were assessed during the 1-year study. Among the GERD patients, 23 displayed a pathological AET (mean, 10.8%), while the others exhibited normal pH. Fifteen of the patients had erosive reflux disease (ERD), including 10 who had an abnormal number of small or large breaks (P<.05). Researchers determined that patients who had an excessive number of esophageal peristalsis breaks, assessed by manometry, had significantly longer prolonged reflux clearance while in the supine position along with greater AET. Patients with ERD exhibited more esophageal breaks, which researchers said, may possibly cause erosions. These findings might explain, if confirmed by outcome studies, that weak peristalsis together with other factors, is involved in the development of erosions of the esophageal mucosa and further confirm the need [for] more effective prokinetic drugs, the researchers concluded. Disclosure: The researchers report no relevant financial disclosures.

have a peek at this website http://www.healio.com/gastroenterology/esophagus/news/online/{f06b1c29-b954-45cf-9c17-bbd50621c458}/supine-gerd-patients-with-large-breaks-experienced-higher-acid-exposure-prolonged-bolus-clearance


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